Perilla
Perilla
Perilla is a plant traditionally used in East Asian medicine, particularly in China, Japan, and Korea. It is known for its culinary uses but has limited traditional medicinal applications noted in historical texts. Scientific studies have identified four characteristic components in Perillae Fructus (fruits of the perilla plant) with correlations between chemical composition and color. Research on Perilla frutescens seed oil showed potential protective effects against cigarette smoke-induced pulmonary inflammation and oxidative stress, though treatment durations and doses varied widely among studies. Additionally, Perilla leaf ethanol extract has been found to preserve the quality of refrigerated snakehead fillets through multiple mechanisms including inhibition of bacterial growth, protection of lipids, and enhancement of sensory acceptance. No major safety issues or drug interactions have been recorded for perilla in current scientific literature.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This study found that Perilla leaf ethanol extract can preserve the quality of refrigerated snakehead fillets through multiple pathways, including inhibiting bacterial growth, protecting lipids, and enhancing sensory acceptance.
- Four QTL regions associated with flower bud differentiation and initial flowering time were identified in Perilla frutescens.
- Four characteristic components were identified as discriminant markers differentiating Perillae Fructus from stir-fried Perillae Fructus.
- The study identified 134 potential BAHD acyltransferase genes in Perilla frutescens, with six candidates prioritized for their role in anthocyanin biosynthesis.
- Thai Perilla frutescens seed oil showed protective effects against cigarette smoke extract-induced lung inflammation and oxidative stress in mice, though treatment durations and doses varied.
- The hot-water extract of defatted Perilla frutescens seed residue suppressed osteoclast differentiation and improved bone-related parameters in ovariectomized mice.
- The study summarized pharmacological activities and genetic/molecular aspects of different chemotypes in Perilla frutescens essential oils, proposing a classification standard.
Frequently asked questions
What is Perilla?
Perilla (Perilla) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Perilla?
7 sourced findings are recorded for Perilla; the strongest carries evidence grade D. For example: This study found that Perilla leaf ethanol extract can preserve the quality of refrigerated snakehead fillets through multiple pathways, including inhibiting bacterial growth, protecting lipids, and enhancing sensory acceptance.
How strong is the evidence for Perilla?
The strongest finding for Perilla carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Perilla safe? What are the side effects?
No major safety issues are recorded for Perilla in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Perilla interact with medications?
No drug interactions are recorded for Perilla in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Perilla?
Perilla is also known as: Перилла, Pérille.
Is Perilla a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Construction of high-density genetic map and QTL mapping of flowering traits in Perilla frutescens. literature abstract metadata
- T2 Pharmacological effects, classification, genetic and molecular studies of different chemotypes essential oil of Perilla frutescens (L.) Britt.: A review. literature abstract metadata
- T2 Exploration on the inhibition effect and pathway of Perilla leaf ethanol extract on flavor deterioration of refrigerated snakehead fillets. literature abstract metadata
- T2 Protective Effect of Thai Perilla frutescens Seed Oil Against Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke Extract in a Mouse Model. literature abstract metadata
- T2 Genome-Wide Identification and Analysis of BAHD Acyltransferases Involved in Anthocyanin Biosynthesis in Perilla frutescens. literature abstract metadata
- T2 Chemical Pattern Recognition and Color-Chromaticity Correlation Analysis for Quality Control of Stir-Fried Perillae Fructus. literature abstract metadata
- T2 Hot-water extract of defatted Perilla frutescens seed residue suppresses osteoclast differentiation and improves bone-related parameters in ovariectomized mice. literature abstract metadata