Carry me seed
Phyllanthus amarus
Phyllanthus amarus, commonly known as Indian gooseberry or bitter lemon, originates from traditional medicine practices in India and other parts of Southeast Asia. It is traditionally used for various ailments such as liver disorders, urinary tract infections, and digestive issues, though specific uses vary among different cultures. Scientific evidence suggests that Phyllanthus amarus leaf extract has shown significant anti-typhoid-like salmonellosis activity due to its bioactive compounds. Additionally, the methanol extract of this plant demonstrated notable in vitro antidiabetic and antioxidant effects through enzyme inhibition and other cellular mechanisms. While it is among the twelve most cited plants for hypoglycemic activity, further validation is required to substantiate these findings. The ethyl acetate fraction from Phyllanthus amarus has also shown promise in reducing histamine release and inflammatory markers in both in vitro and mouse models of allergy. Safety records indicate no major issues have been recorded, and there are currently no known drug interactions associated with this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Phyllanthus amarus leaf extract demonstrated significant anti-typhoid-like salmonellosis activity through multiple bioactive compounds.
- Phyllanthus amarus methanol extract showed notable in vitro antidiabetic and antioxidant activity through enzyme inhibition, cellular effects, and bioactive compound identification.
- Phyllanthus amarus was among the twelve most cited plants with notable hypoglycemic activity but requires further scientific validation.
- The ethyl acetate fraction from Phyllanthus amarus reduced histamine release and inflammatory markers in both in vitro and mouse models of allergy.
- The study identified Phyllanthus amarus compounds with potential as WNT5A modulators in ovarian cancer, based on computational analyses.
Frequently asked questions
What is Carry me seed?
Carry me seed (Phyllanthus amarus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Carry me seed?
5 sourced findings are recorded for Carry me seed; the strongest carries evidence grade D. For example: Phyllanthus amarus leaf extract demonstrated significant anti-typhoid-like salmonellosis activity through multiple bioactive compounds.
How strong is the evidence for Carry me seed?
The strongest finding for Carry me seed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Carry me seed safe? What are the side effects?
No major safety issues are recorded for Carry me seed in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Carry me seed interact with medications?
No drug interactions are recorded for Carry me seed in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Carry me seed?
Carry me seed is also known as: Casse-pierre.
Is Carry me seed a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Diabetes mellitus in ECOWAS: an overview of the safety and efficacy of medicinal plants used in traditional medicine practices. literature abstract metadata
- T2 Unlocking the Antidiabetic and Antioxidant Potentials of Phyllanthus amarus Using In Vitro and In Silico Approaches. literature abstract metadata
- T2 Anti-typhoid-like salmonellosis activity of Phyllanthus amarus Schum. & Thonn. (Phyllanthaceae) leaves extract: UHPLC-ESI-DAD-MS profiling, in vitro and in vivo efficacy assessment, and molecular dynamics simulations targeting SseK3. literature abstract metadata
- T2 Integrative transcriptomics and structure-based screening identifies Phyllanthus amarus phytocompounds as potential WNT5A modulators in ovarian cancer. literature abstract metadata
- T2 The Role of Ethyl Acetate Fraction from Phyllanthus amarus in Down-Regulation of Allergic Inflammatory Responses. literature abstract metadata