Gale of The Wind
Phyllanthus niruri
Phyllanthus niruri, a plant traditionally used in various folk medicine practices but with no specific recorded traditional uses, has shown promising results in scientific studies. Research indicates that PHYLN-NIO can reduce obesity-induced hepatic steatosis and inflammation in rats through modulating MALAT1/miR-206/GLP-1R signaling pathways. Additionally, it demonstrated significant improvement in kidney function markers and histopathology in diabetic/nephrotoxic rat models. A combination extract of Blumea balsamifera, Anredera cordifolia, and Phyllanthus niruri showed notable anti-inflammatory activity across multiple platforms. Scientific evidence suggests that this plant may be effective for certain conditions, though more human studies are needed to confirm these findings. No major safety issues or drug interactions have been recorded, but further research is warranted to fully understand its potential benefits and applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- PHYLN-NIO reduced obesity-induced hepatic steatosis and inflammation while improving lipid profiles in rats.
- Phyllanthus niruri, as part of a herbal extract combination, showed significant improvement in kidney function markers and histopathology in diabetic/nephrotoxic rats.
- Phyllanthus niruri showed significantly higher reported effectiveness than most other treatments, including allopurinol, tamsulosin, hydrochlorothiazide, and potassium citrate, across three platforms.
- The study found that a combination extract of Blumea balsamifera, Anredera cordifolia, and Phyllanthus niruri showed significant anti-inflammatory activity.
Frequently asked questions
What is Gale of The Wind?
Gale of The Wind (Phyllanthus niruri) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Gale of The Wind?
4 sourced findings are recorded for Gale of The Wind; the strongest carries evidence grade D. For example: PHYLN-NIO reduced obesity-induced hepatic steatosis and inflammation while improving lipid profiles in rats.
How strong is the evidence for Gale of The Wind?
The strongest finding for Gale of The Wind carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Gale of The Wind safe? What are the side effects?
No major safety issues are recorded for Gale of The Wind in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Gale of The Wind interact with medications?
No drug interactions are recorded for Gale of The Wind in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Gale of The Wind?
Gale of The Wind is also known as: Phyllanthe de Nirur.
Is Gale of The Wind a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Formulation of Blumea balsamifera, Anredera cordifolia, and Phyllanthus niruri Extracts as Potential Anti-Inflammatory Agents. literature abstract metadata
- T2 Phyllanthus niruri niosomes ameliorate obesity-induced hepatic steatosis in rats via modulating MALAT1/miR-206/GLP-1R signaling and hepatic lipid metabolism. literature abstract metadata
- T2 AI-driven credibility profiling of real-world patient experiences suggests overlooked kidney stone therapies warrant further investigation. literature abstract metadata
- T2 Nephroprotective and antioxidant properties of a novel herbal extract combination in a high-fat diet and alloxan-induced kidney injury in rats. literature abstract metadata