dragon-of-the-world
Phyllanthus pulcher
Phyllanthus pulcher is an herb traditionally used with limited documentation. Scientific studies have shown that its aerial parts, particularly when processed into a DCM extract, exhibit significant anticancer activity against prostate cancer cell lines. Additionally, research indicates that salicylic acid and certain phenol derivatives from related plants may play a role in enhancing bioactive compounds. Two compounds identified from Sphingomonas sanguinis DM demonstrated moderate antimicrobial and cytotoxic activities. The plant also showed moderate anti-angiogenic activity in assays. No major safety concerns or recorded drug interactions have been noted, but further research is needed to fully understand its potential benefits and risks.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The DCM extract of Phyllanthus pulcher aerial parts showed significant anticancer activity against DU-145 prostate cancer cell lines.
- The study found that salicylic acid 50 μM significantly increased phenol and phenylpropanoid derivatives in Phyllanthus acuminatus hairy roots.
- The study identified two compounds from Sphingomonas sanguinis DM with moderate antimicrobial and cytotoxic activities.
- Phyllanthus pulcher, among other plants, showed moderate anti-angiogenic activity in the rat aortic ring assay.
Frequently asked questions
What is dragon-of-the-world?
dragon-of-the-world (Phyllanthus pulcher) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about dragon-of-the-world?
4 sourced findings are recorded for dragon-of-the-world; the strongest carries evidence grade D. For example: The DCM extract of Phyllanthus pulcher aerial parts showed significant anticancer activity against DU-145 prostate cancer cell lines.
How strong is the evidence for dragon-of-the-world?
The strongest finding for dragon-of-the-world carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is dragon-of-the-world safe? What are the side effects?
No major safety issues are recorded for dragon-of-the-world in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does dragon-of-the-world interact with medications?
No drug interactions are recorded for dragon-of-the-world in our sources. This does not rule them out — check with a pharmacist.
Is dragon-of-the-world a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Anti-angiogenic and cytotoxicity studies of some medicinal plants. literature abstract metadata
- T2 Anticancer properties and phenolic contents of sequentially prepared extracts from different parts of selected medicinal plants indigenous to Malaysia. literature abstract metadata
- T2 Evaluation of Salicylic Acid and Methyl Jasmonate as Elicitors in Phyllanthus acuminatus Hairy Roots by Non-Targeted Analysis Using High-Resolution Mass Spectrometry. literature abstract metadata
- T2 Phytochemical and biological assessment of secondary metabolites isolated from a rhizosphere strain, Sphingomonas sanguinis DM of Datura metel. literature abstract metadata