Phyllanthus taxodiifolius
Phyllanthus taxodiifolius
Phyllanthus taxodiifolius is a plant traditionally not associated with any specific medicinal use. Scientific studies have shown promising results, indicating that extracts from this plant may possess anti-cancer properties, particularly in glioblastoma cells, by reducing certain cellular structures and activities involved in tumor growth and invasion. M3, a lignan xyloside derived from Phyllanthus taxodiifolius, demonstrated potent antiproliferative and pro-apoptotic effects on HCT116 cells, while ECDD-S16 inhibited pyroptosis in Raw264.7 cells by interfering with V-ATPase activity. Additionally, extracts suppressed the invasive properties of glioblastoma cells through microtubule disruption. To date, no significant safety issues or drug interactions have been recorded for Phyllanthus taxodiifolius, but further research is needed to fully understand its potential benefits and applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- M3, a lignan xyloside from Phyllanthus taxodiifolius, showed potent antiproliferative and pro-apoptotic effects in HCT116 cells.
- Phyllanthus taxodiifolius extract reduced N-cadherin, vimentin expression, paxillin activation, and actin stress fibers in glioblastoma cells.
- Phyllanthus taxodiifolius extract suppressed invasive properties of glioblastoma cells by disrupting microtubule dynamics.
- ECDD-S16, a derivative from Phyllanthus taxodiifolius, can inhibit pyroptosis in Raw264.7 cells by interfering with endosome acidification.
Frequently asked questions
What is Phyllanthus taxodiifolius?
Phyllanthus taxodiifolius (Phyllanthus taxodiifolius) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Phyllanthus taxodiifolius?
4 sourced findings are recorded for Phyllanthus taxodiifolius; the strongest carries evidence grade D. For example: M3, a lignan xyloside from Phyllanthus taxodiifolius, showed potent antiproliferative and pro-apoptotic effects in HCT116 cells.
How strong is the evidence for Phyllanthus taxodiifolius?
The strongest finding for Phyllanthus taxodiifolius carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Phyllanthus taxodiifolius safe? What are the side effects?
No major safety issues are recorded for Phyllanthus taxodiifolius in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Phyllanthus taxodiifolius interact with medications?
No drug interactions are recorded for Phyllanthus taxodiifolius in our sources. This does not rule them out — check with a pharmacist.
Is Phyllanthus taxodiifolius a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 M3, a natural lignan xyloside, exhibits potent anticancer activity in HCT116 cells. literature abstract metadata
- T2 Phyllanthus taxodiifolius Beille suppresses microtubule dynamics and restricts glioblastoma aggressiveness. literature abstract metadata
- T2 Phyllanthus taxodiifolius Beille Disrupted N-cadherin, Vimentin, Paxillin and Actin Stress Fibers in Glioblastoma. literature abstract metadata
- T2 ECDD-S16 targets vacuolar ATPase: A potential inhibitor compound for pyroptosis-induced inflammation. literature abstract metadata