Phyllanthus taxodiifolius
Phyllanthus taxodiifolius
Phyllanthus taxodiifolius is a plant that has not been traditionally used in any known medicinal practices. Scientific studies have shown promising results, with M3, a lignan xyloside from this plant, exhibiting potent antiproliferative and pro-apoptotic effects in HCT116 cells. Additionally, extracts of Phyllanthus taxodiifolius have been found to reduce N-cadherin, vimentin expression, paxillin activation, and actin stress fibers in glioblastoma cells, thereby suppressing their invasive properties by disrupting microtubule dynamics. Another derivative, ECDD-S16, has demonstrated the ability to inhibit pyroptosis in Raw264.7 cells by interfering with endosome acidification. To date, no major safety issues or drug interactions have been recorded for Phyllanthus taxodiifolius.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- M3, a lignan xyloside from Phyllanthus taxodiifolius, showed potent antiproliferative and pro-apoptotic effects in HCT116 cells.
- Phyllanthus taxodiifolius extract reduced N-cadherin, vimentin expression, paxillin activation, and actin stress fibers in glioblastoma cells.
- Phyllanthus taxodiifolius extract suppressed invasive properties of glioblastoma cells by disrupting microtubule dynamics.
- ECDD-S16, a derivative from Phyllanthus taxodiifolius, can inhibit pyroptosis in Raw264.7 cells by interfering with endosome acidification.
Frequently asked questions
What is Phyllanthus taxodiifolius?
Phyllanthus taxodiifolius (Phyllanthus taxodiifolius) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Phyllanthus taxodiifolius?
4 sourced findings are recorded for Phyllanthus taxodiifolius; the strongest carries evidence grade D. For example: M3, a lignan xyloside from Phyllanthus taxodiifolius, showed potent antiproliferative and pro-apoptotic effects in HCT116 cells.
How strong is the evidence for Phyllanthus taxodiifolius?
The strongest finding for Phyllanthus taxodiifolius carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Phyllanthus taxodiifolius safe? What are the side effects?
No major safety issues are recorded for Phyllanthus taxodiifolius in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Phyllanthus taxodiifolius interact with medications?
No drug interactions are recorded for Phyllanthus taxodiifolius in our sources. This does not rule them out — check with a pharmacist.
Is Phyllanthus taxodiifolius a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 M3, a natural lignan xyloside, exhibits potent anticancer activity in HCT116 cells. literature abstract metadata
- T2 Phyllanthus taxodiifolius Beille suppresses microtubule dynamics and restricts glioblastoma aggressiveness. literature abstract metadata
- T2 Phyllanthus taxodiifolius Beille Disrupted N-cadherin, Vimentin, Paxillin and Actin Stress Fibers in Glioblastoma. literature abstract metadata
- T2 ECDD-S16 targets vacuolar ATPase: A potential inhibitor compound for pyroptosis-induced inflammation. literature abstract metadata