black pepper
Piper nigrum
黑胡椒（Piper nigrum）起源于东南亚的传统医学实践。其使用记录并不广泛；然而，它被用于烹饪和芳香目的。科学证据表明，结构修饰的胡椒碱衍生物可能具有作为抗癌剂的潜力，尽管这些结论是初步的，并需要进一步研究来证实这些效果。此外，胡椒碱-琥珀酸盐纳米共晶在雄性Wistar大鼠血清中显示出显著降低胆固醇和甘油三酯水平，表明可能的心血管益处。该研究还鉴定出某些链霉菌株可以控制 Phytophthora capsici 并促进黑胡椒生长。胡椒碱被发现能够调节DNA甲基化、组蛋白乙酰化和microRNA网络，暗示其作为表观遗传学调节剂在癌症和慢性疾病中的潜在作用，但需要进一步研究以应用于临床。迄今为止，没有记录到与黑胡椒相关的重大安全问题或药物相互作用，尽管这些结论基于有限的数据。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 胡椒碱-琥珀酸钠纳米共晶显著降低了雄性Wistar大鼠血清胆固醇和甘油三酯水平，与未处理的胡椒碱相比。
- 研究发现，Streptomyces minutiscleroticus 和 S. longisporoflavus 具有控制 Phytophthora capsici 及促进黑胡椒生长的潜力。
- 近期研究表明，从黑胡椒（Piper nigrum）中获得的结构修饰的去氧 Piperine 衍生物表现出作为抗癌剂增强的潜力。
- 胡椒碱调节DNA甲基化、组蛋白乙酰化和microRNA网络，显示出作为癌症和慢性疾病表观遗传调节剂的潜力。
- 研究发现，由Phytophthora capsici引起的病原体感染会导致黑胡椒中的m⁶A修饰发生变化，这可能与防御反应有关。
Frequently asked questions
What is black pepper?
black pepper (Piper nigrum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about black pepper?
5 sourced findings are recorded for black pepper; the strongest carries evidence grade D. For example: 胡椒碱-琥珀酸钠纳米共晶显著降低了雄性Wistar大鼠血清胆固醇和甘油三酯水平，与未处理的胡椒碱相比。
How strong is the evidence for black pepper?
The strongest finding for black pepper carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is black pepper safe? What are the side effects?
No major safety issues are recorded for black pepper in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does black pepper interact with medications?
No drug interactions are recorded for black pepper in our sources. This does not rule them out — check with a pharmacist.
What are the common names of black pepper?
black pepper is also known as: черный перец, poivre.
Is black pepper a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Unleashing the biocontrol and plant growth promoting potential of native rhizosphere Streptomyces spp. against Phytophthora foot rot in black pepper (Piper nigrum L.). literature abstract metadata
- T2 Pathogen-triggered m⁶A epitranscriptomic reprogramming is linked to host defense responses in the Piper nigrum-Phytophthora capsici pathosystem. literature abstract metadata
- T2 Recent advances in piperine and its derivatives as potential anticancer agents. literature abstract metadata
- T2 Nano-cocrystals of piperine-succinic acid and its antihyperlipidemic effect in male Wistar rats. literature abstract metadata
- T2 Piperine as a Multifunctional Epigenetic Modulator: Integrative Molecular Insights into Cancer and Chronic Disease Therapy. literature abstract metadata