Piper wallichii
Piper wallichii
Piper wallichii，又称印度长辣椒，在阿育吠陀医学中传统上被使用。尽管其在烹饪以外的特定传统用途方面没有广泛记录，但研究显示了令人鼓舞的结果。科学证据表明，Piper wallichii 的乙醇提取物通过调节炎症和免疫因子改善了 DSS 诱导的小鼠溃疡性结肠炎的症状。此外，从植物中分离出的一种石油醚分数被发现激活自噬、延长寿命并表现出抗阿尔茨海默病效应，在 C. elegans 模型中显示出抗失忆作用，尽管这些效应依赖于特定的基因参与自噬诱导。还从该植物中鉴定出了两种具有抗菌活性的新化合物。从 Piper wallichii 中分离出的瓦尔希金因增强了某些药物对癌细胞的效果，通过抑制 ABCB1 的外排活动而不改变其表达。迄今为止尚未记录到 Piper wallichii 造成的主要安全问题或已知药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从瓦莱里安胡椒中提取的乙醇提取物通过影响炎症和免疫因子改善了由DSS诱导的小鼠溃疡性结肠炎的症状。
- 来自Piper wallichii的石油醚分数延长了C. elegans 的寿命并改善了健康跨度，通过激活自噬作用显示出抗衰老和抗AD效应的潜力。
- Wallichinine enhances the effects of certain ABCB1 substrates on cancer cells without altering sensitivity to non-substrates, by blocking ABCB1's drug-efflux activity.
- 从乌尔希胡椒中鉴定出两种新的化合物，对某些病原体具有较弱的抗菌活性。
Frequently asked questions
What is Piper wallichii?
Piper wallichii (Piper wallichii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Piper wallichii?
4 sourced findings are recorded for Piper wallichii; the strongest carries evidence grade D. For example: 从瓦莱里安胡椒中提取的乙醇提取物通过影响炎症和免疫因子改善了由DSS诱导的小鼠溃疡性结肠炎的症状。
How strong is the evidence for Piper wallichii?
The strongest finding for Piper wallichii carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Piper wallichii safe? What are the side effects?
No major safety issues are recorded for Piper wallichii in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Piper wallichii interact with medications?
No drug interactions are recorded for Piper wallichii in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Piper wallichii?
Piper wallichii is also known as: Poivrier de Wallich.
Is Piper wallichii a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Wallichinine reverses ABCB1-mediated cancer multidrug resistance. literature abstract metadata
- T2 Chemical constituents and antibacterial activity from the stems and leaves of Piper wallichii. literature abstract metadata
- T2 Ethanol extract of Piper wallichii ameliorates DSS-induced ulcerative colitis in mice: Involvement of TLR4/NF-κB/COX-2 signaling pathway. literature abstract metadata
- T2 Targeting autophagy to discover the Piper wallichii petroleum ether fraction exhibiting antiaging and anti-Alzheimer's disease effects in Caenorhabditis elegans. literature abstract metadata