Piper wallichii
Piper wallichii
Piper wallichii，传统上称为印度长胡椒，是一种原产于喜马拉雅地区的植物，并在传统的阿育吠陀医学中使用。尽管其具体用途尚未充分记录，但研究表明其乙醇提取物可能通过调节炎症和免疫因子来改善由DSS诱导的小鼠溃疡性结肠炎的症状。此外，从该植物中分离出的石油醚部分延长了秀丽隐杆线虫的寿命并改善了健康状况，这表明其具有抗衰老和神经退行性疾病潜力。从植物中分离出的瓦利辛碱增强了某些ABCB1底物对癌细胞的效果，而不改变非底物的敏感性，可能是通过阻断ABCB1的药物外排作用。还鉴定出了两种新的具有特定病原体弱抗菌活性的新化合物。Piper wallichii的安全性和药物相互作用数据有限，并未记录到重大问题或交互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从瓦莱里安胡椒中提取的乙醇提取物通过影响炎症和免疫因子改善了由DSS诱导的小鼠溃疡性结肠炎的症状。
- 来自Piper wallichii的石油醚分数延长了C. elegans 的寿命并改善了健康跨度，通过激活自噬作用显示出抗衰老和抗AD效应的潜力。
- Wallichinine增强某些ABCB1底物在癌细胞中的作用，而不改变对非底物的敏感性，因其阻断了ABCB1的药物外排活性。
- 从乌尔希胡椒中鉴定出两种新的化合物，对某些病原体具有较弱的抗菌活性。
Frequently asked questions
What is Piper wallichii?
Piper wallichii (Piper wallichii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Piper wallichii?
4 sourced findings are recorded for Piper wallichii; the strongest carries evidence grade D. For example: 从瓦莱里安胡椒中提取的乙醇提取物通过影响炎症和免疫因子改善了由DSS诱导的小鼠溃疡性结肠炎的症状。
How strong is the evidence for Piper wallichii?
The strongest finding for Piper wallichii carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Piper wallichii safe? What are the side effects?
No major safety issues are recorded for Piper wallichii in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Piper wallichii interact with medications?
No drug interactions are recorded for Piper wallichii in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Piper wallichii?
Piper wallichii is also known as: Poivrier de Wallich.
Is Piper wallichii a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Wallichinine reverses ABCB1-mediated cancer multidrug resistance. literature abstract metadata
- T2 Chemical constituents and antibacterial activity from the stems and leaves of Piper wallichii. literature abstract metadata
- T2 Ethanol extract of Piper wallichii ameliorates DSS-induced ulcerative colitis in mice: Involvement of TLR4/NF-κB/COX-2 signaling pathway. literature abstract metadata
- T2 Targeting autophagy to discover the Piper wallichii petroleum ether fraction exhibiting antiaging and anti-Alzheimer's disease effects in Caenorhabditis elegans. literature abstract metadata