Angelicas
Angelica
Angelica is a traditional plant used in various herbal practices. It has been traditionally utilized in Chinese medicine for its purported benefits such as aiding digestion and promoting blood circulation, though specific uses vary among different traditions. Scientific evidence suggests that Angelica sinensis polysaccharides can be enhanced through electron beam irradiation, which may modify their biofunctional properties. Nanoparticles derived from Angelica (DAZ NPs) have shown potential in enhancing the stability and bioaccessibility of dioscin, a compound found within the plant, while also supporting hepatocyte viability. Metabolomic and transcriptomic analyses indicate differences between wild and cultivated Angelica sinensis, with wild plants displaying higher levels of certain compounds. While studies suggest that Angelica root might be associated with adverse events in GLP-1 receptor agonist (GLP-1 RA) therapy, these findings are currently exploratory and require further investigation. No major safety concerns or known drug interactions have been recorded for Angelica.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Electron beam irradiation enhanced extraction yield and modified the biofunctional properties of Angelica sinensis polysaccharides in a dose-dependent manner.
- DAZ NPs enhanced dioscin's stability, bioaccessibility, and hepatocyte viability compared to free dioscin.
- Metabolomic and transcriptomic analyses revealed differences in metabolic profiles between wild and cultivated Angelica sinensis, with wild plants showing higher levels of certain compounds.
- Angelica dahurica polysaccharide alleviated hippocampal damage induced by ovariectomy/galactose in rats by enhancing antioxidant capacity and regulating metabolic pathways.
- The study identified Angelica root as one of several herbs potentially associated with adverse events in GLP-1 RA therapy, though findings are exploratory.
- Angelica dahurica extract alleviated muscle atrophy after nerve injury in rats, independently of its analgesic effects.
- Angelica sinensis treatment dose-dependently promoted thymic cortical regeneration in mice with acute thymic involution induced by rapamycin.
Frequently asked questions
What is Angelicas?
Angelicas (Angelica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Angelicas?
7 sourced findings are recorded for Angelicas; the strongest carries evidence grade D. For example: Electron beam irradiation enhanced extraction yield and modified the biofunctional properties of Angelica sinensis polysaccharides in a dose-dependent manner.
How strong is the evidence for Angelicas?
The strongest finding for Angelicas carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Angelicas safe? What are the side effects?
No major safety issues are recorded for Angelicas in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Angelicas interact with medications?
No drug interactions are recorded for Angelicas in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Angelicas?
Angelicas is also known as: Дудник, Angélique.
Is Angelicas a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Nano-assembly of dioscin via zein-Angelica sinensis polysaccharide composite nanocarriers: structure, stability, bioaccessibility and bioactivity. literature abstract metadata
- T2 Efficiently electron beam radiation-induced degradation and extraction of Angelica sinensis polysaccharides and its excellent biofunctional properties. literature abstract metadata
- T2 Integrated metabolomics and transcriptomics reveal metabolite differences between wild and cultivated Angelica sinensis. literature abstract metadata
- T2 [Angelica sinensis promotes thymic cortical regeneration in mice with acute thymic involution induced by short-term rapamycin treatment]. literature abstract metadata
- T2 Angelica dahurica alleviates peripheral nerve injury-induced muscle atrophy via the Phlpp2-Akt-FoxO3α axis independently of analgesia. literature abstract metadata
- T2 Protective effects of Angelica dahurica polysaccharide on alleviating hippocampus injury induced by ovariectomized/D-galactose in rats by inhibiting oxidative stress and its serum metabolomics. literature abstract metadata
- T2 Real-world and computational identification of herbal candidates associated with adverse event patterns in glucagon-like peptide-1 therapy for obesity. literature abstract metadata