Coastal angelica, Japanese angelica
Angelica japonica
Angelica japonica is a plant native to East Asia and has been studied for its potential medicinal properties. While traditional uses are not well-documented, scientific research indicates that it contains nicotinic acid N-glucoside along with other compounds found in related species. In one study, the essential oil of Angelica dahurica (which is closely related) showed significant toxicity against Aedes aegypti larvae, though this finding does not directly apply to Angelica japonica itself. Additionally, 3'-O-Acetylhamaudol from its roots demonstrated anti-tumor effects through anti-angiogenic actions and immune system modulation. Further, japoangelone and related compounds isolated from the plant showed some inhibitory activity against cancer cell growth. Safety data for Angelica japonica is currently limited but no major issues have been recorded. There are also no reported drug interactions as of now.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Angelica japonica forms nicotinic acid N-glucoside along with seven other plant species in this study.
- 3'-O-Acetylhamaudol from Angelica japonica roots showed anti-tumor effects via anti-angiogenic actions and immune system modulation.
- The study found that Angelica dahurica essential oil had a significant toxic effect against Aedes aegypti larvae, with LC₅₀ and LC₉₀ values provided.
- The CHCl3 extract from Angelica japonica root showed high inhibitory activity against human gastric adenocarcinoma cells.
Frequently asked questions
What is Coastal angelica, Japanese angelica?
Coastal angelica, Japanese angelica (Angelica japonica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Coastal angelica, Japanese angelica?
4 sourced findings are recorded for Coastal angelica, Japanese angelica; the strongest carries evidence grade D. For example: Angelica japonica forms nicotinic acid N-glucoside along with seven other plant species in this study.
How strong is the evidence for Coastal angelica, Japanese angelica?
The strongest finding for Coastal angelica, Japanese angelica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Coastal angelica, Japanese angelica safe? What are the side effects?
No major safety issues are recorded for Coastal angelica, Japanese angelica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Coastal angelica, Japanese angelica interact with medications?
No drug interactions are recorded for Coastal angelica, Japanese angelica in our sources. This does not rule them out — check with a pharmacist.
Is Coastal angelica, Japanese angelica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Anti-tumor actions of major component 3'-O-acetylhamaudol of Angelica japonica roots through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation. literature abstract metadata
- T2 Immunotoxicity activity from various essential oils of Angelica genus from South Korea against Aedes aegypti L. literature abstract metadata
- T2 Comparison of the formation of nicotinic acid conjugates in leaves of different plant species. literature abstract metadata
- T2 Antiproliferative constituents from umbelliferae plants. V. A new furanocoumarin and falcarindiol furanocoumarin ethers from the root of Angelica japonica. literature abstract metadata