Damask rose
Rosa × damascena
Rosa × damascena, commonly known as the rose, is a traditional plant used in various cultural and aesthetic practices. It has been traditionally employed for its aromatic properties and ornamental value but lacks specific documented uses in medicinal traditions. Scientific evidence suggests that Rosa × damascena callus-derived exosome-like vesicles (RSC-EXO) may have potential benefits for skin health, including improved biocompatibility, increased collagen synthesis, reduced melanin production, and suppressed inflammatory cytokine secretion. Additionally, the plant's phytochemical compounds are reported to alter smooth muscle contractility. A study indicated that Rosa × damascena extract could show a statistically significant reduction in depression scores compared to placebo groups. The aroma components of rose hydrosols have also been quantified using reversed-phase HPLC with hydroxypropyl-β-cyclodextrin, identifying eight characteristic aroma components. Safety profiles for the plant are generally favorable with no major issues recorded, and there is no reported evidence of significant drug interactions.
- Best evidence
- B
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Rosa damascena callus-derived exosome-like vesicles (RSC-EXO) showed improved biocompatibility, increased collagen synthesis, reduced melanin production, and suppressed inflammatory cytokine secretion in skin-related cellular models.
- Rosa damascena and its phytochemical compounds alter the contractile properties of various smooth muscles.
- The study found that Rosa damascena extract showed a statistically significant reduction in depression scores compared to the placebo group.
- The study successfully quantified eight characteristic aroma components in rose hydrosols using reversed-phase HPLC with hydroxypropyl-β-cyclodextrin.
- The study identified key structural proteins and transcription factors involved in anthocyanin biosynthesis in edible rose varieties.
- The study found that liposomal nano-encapsulated Rosa damascena callus extract showed significant improvement in wound healing without skin toxicity in animal models.
Frequently asked questions
What is Damask rose?
Damask rose (Rosa × damascena) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Damask rose?
6 sourced findings are recorded for Damask rose; the strongest carries evidence grade B. For example: Rosa damascena callus-derived exosome-like vesicles (RSC-EXO) showed improved biocompatibility, increased collagen synthesis, reduced melanin production, and suppressed inflammatory cytokine secretion in skin-related cellular models.
How strong is the evidence for Damask rose?
The strongest finding for Damask rose carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Damask rose safe? What are the side effects?
No major safety issues are recorded for Damask rose in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Damask rose interact with medications?
No drug interactions are recorded for Damask rose in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Damask rose?
Damask rose is also known as: Роза дамасская, Rosier de Damas.
Is Damask rose a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Effect of oral capsules of Rosa damascena mill extract on depression, anxiety and stress in menopausal women: A randomized controlled trial. literature abstract metadata
- T2 Effects of Rosa damascena and its compounds on smooth muscle contractility. literature abstract metadata
- T2 Machine learning integrates metabolomics and proteomics to identify key regulators of anthocyanin biosynthesis in edible rose petals. literature abstract metadata
- T2 Quantitative analysis of characteristic aroma components in rose hydrosol by reversed-phase liquid chromatography using hydroxypropyl-β-cyclodextrin as mobile-phase additive. literature abstract metadata
- T2 From Plant to Nano-Clinic: Advancing Wound Healing with Nano- Encapsulated Rosa damascena Callus Extract. literature abstract metadata
- T2 Characterization of Rosa damascena Callus-Derived Exosome-like Vesicles and Their Multifunctional Activities in Skin-Related Cellular Models. literature abstract metadata